FALL - New Commencement of Pediatric Clinical Trial for Soliris

[Linda Burke]

As part of Alexion Pharmaceutical's second quarter review, the following information was released this week:

Because we are keenly aware that aHUS frequently affects children, often with devastating consequences, we are working expeditiously to expand our aHUS development program to include pediatric patients. As you may be aware, there is a requirement in Europe to submit a formal Pediatric Investigational Plan defining a sponsor’s clinical development program across all pediatric age groups. Based on the regulatory feedback we have received on this Plan, we are now preparing to commence our pediatric aHUS study this fall [in the United States and other countries].

You'll note that the pediatric clinical trial for Soliris now has a fall timeframe, for the reasons described above. I have no further verifiable information to release at this juncture, but will keep you posted when further information comes my way. You are welcome to email any breaking news (complete with source notations for verification purposes) to me at [e-mail] .

[Cheryl Biermann]

Thank you for the hours of work you do Linda, to get this information to the aHUS family!

[Jessica Olivia Frysz]

Thank you so much for the news :) That's good they are going to work on a trial, because I think this drug will do good for patients with aHUS including myself, who is also looking to receive a kidney transplant :)

[Svetlana Finley]

Thanks for the news ;-)