I was diagnosed with aHUS about 16 years back and have been on dialysis ever since with an unsuccessful transplant about 15 years back.
I am currently on daily nocturnal home hemo. I use 10,000 units of heparin. Suddenly my platelets have plummeted to 31,000! There have been no symptoms of a low platelet count. I repeated the test and the value is right. My hemoglobin is 11.8 and WBCs are 2,700 (my WBCs have always been around that). I have been asked to run tonight heparin free which means I would need to flush 100 ml of saline every hour which is a huge pain.
But the larger question is still unanswered - why would my platelets fall so much so suddenly? Could this be related to the aHUS in any way? My neph has asked me to test my LDH, Reticulocyte count, Blood film and then if necessary check for Heparin Induced Thrombocytopenia Antibodies.